Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans

ABSTRACT Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills more than 180,000 people annually.Contributing to its success as a fungal pathogen is its cell wall surrounded by a capsule.When the cryptococcal cell wall is compromised, exposed pathogen-associated molecular pattern molecules (PAMPs) could trigger host

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Efficacy and safety of Naoxintong capsule for treating chronic stable angina: study protocol for a randomized controlled trial

Abstract Background Cardiovascular disease is the leading cause of mortality and morbidity worldwide, Chronic stable angina (CSA) is the main symptom of myocardial ischemia, causes increased risk of major cardiovascular events such as sudden cardiac death and myocardial infarction.Naoxintong (NXT) capsule is a classical traditional Chinese medicati

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Women in Conflict

This article focuses on female combatants serving in armed conflicts in Africa, South America, and Asia, profiling their time engaged with these forcesas well as the realities they face upon their return to civilian life.Women play a significant role in these conflicts, sometimes constituting up to 30% of the armed forces, although they are often o

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